Mixer Settler
The Mixer Settler system provides a highly controllable platform for liquid-liquid extraction, combining high‑visibility borosilicate glass with precisely engineered hydrodynamics. Designed for chemists and process engineers who need predictable phase behaviour, the systems deliver efficient mixing, clean phase disengagement, and reliable scale‑up from laboratory to pilot operations. Their transparent construction and robust PTFE internals make them ideal for optimisation, troubleshooting, and high‑purity separations across a wide range of solvent systems.
Specifications
Volume*
Mixer: 100 ml – 5000 ml
Settler: 200 ml – 10’000 ml
Operating temperature
-20°C to +200 °C
(typical operating temperature range +20°C to +80 °C)
Vessel type
Single wall, double wall
Operating pressure
Operating pressure
Separation time
Suitable for both short extraction times (0.5 – 15 min) and long extraction times (>15 min) **
Multi-step
Systems can be used in single more or sequentially for multi-step processes**
Coating options
Breakage protection, Antistatic
Wetted materials
Borosilicate glass 3.3, PTFE (SS316L and Hastelloy options available)
*custom sizes available
**discuss your process with our in-house specialists to define correct configuration
The mixer–settler operates in two integrated stages. In the mixing chamber, controlled agitation disperses one liquid phase into the other, creating a consistent droplet size distribution that maximises mass transfer without excessive shear. The geometry of the chamber, combined with carefully selected impeller options, ensures efficient contact between phases while minimising emulsion formation.
Once mixed, the dispersion flows into the settling zone, where the phases separate under gravity. Adjustable overflow ports allow precise control of the interface, ensuring clean withdrawal of both light and heavy phases. The transparent borosilicate body enables real‑time observation of droplet coalescence, interface stability, and separation quality, making optimisation intuitive and fast. Optional tempering jackets provide thermal control for temperature‑sensitive extractions.
Mixer–settlers from GlasKeller are widely used in fine chemical synthesis, pharmaceutical development, natural product purification, hydrometallurgical separations, and solvent recovery. Their clarity and controllability make them especially valuable in R&D environments where understanding phase behaviour is essential for scale‑up and process design.
Beyond their versatility, these systems offer strong operational advantages: predictable hydrodynamics, reproducible separations, and rapid troubleshooting thanks to full visual access. The chemically resistant construction supports aggressive solvents, while the modular design allows easy cleaning, maintenance, and configuration for multi‑stage cascades. Together, these benefits provide a dependable, insight‑rich platform for developing and refining extraction processes.
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Whether you are an existing customer looking to reproduce your glassware or someone with an entirely new challenge, we deliver unbeatable product quality and excellent support from enquiry to delivery, and beyond.
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